
刘玉胜教授,主要研究方向为“RNA转录后调控:Poly(A)尾巴和可变剪切的动态变化、功能和调控机制”,在Nature Structural & Molecular Biology,Nature Communications,Nature Protocols等期刊发表论文10+篇,授权国家专利2项并转化1项。E-mail:liuys1126@foxmail.com
代表性成果(# first authors; * corresponding authors)
1. Yusheng Liu#*, Wenrong Tao#, Shuang Wu#, Yiwei Zhang, Hu Nie, Zhenzhen Hou, Jingye Zhang, Zhen Yang, Zi-Jiang Chen, Jiaqiang Wang*, Falong Lu*, Keliang Wu*. Maternal mRNA deadenylation is defective in in vitro matured mouse and human oocytes. Nature Communications, 2024, 15(1):5550.
2. Jiaqiang Wang*, Yiwei Zhang, Jiaze Gao, Guihai Feng, Chao Liu, Xueke Li, Pengcheng Li, Zhonghua Liu, Falong Lu, Leyun Wang*, Wei Li*, Qi Zhou*, Yusheng Liu*. Alternative splicing of CARM1 regulated by LincGET-guided paraspeckles biases the first cell fate in mammalian early embryos. Nature Structural & Molecular Biology, 2024, 31(9):1341-1354.
3. Yusheng Liu#, Keliang Wu#, Fanghong Shao#, Hu Nie, Jingye Zhang, Cheng Li, Zhenzhen Hou, Jiaqiang Wang*, Bing Zhou*, Han Zhao*, Falong Lu*. Remodeling of maternal mRNA through poly(A) tail orchestrates human oocyte-to-embryo transition. Nature Structural & Molecular Biology, 2023, 30(2): 200-215.
4. Yusheng Liu*, Yiwei Zhang, Jiaqiang Wang*, Falong Lu*. Transcriptome-wide measurement of poly(A) tail length and composition at sub-nanogram total RNA sensitivity by PAIso-seq. Nature Protocols, 2022, 17, 1980-2007.