
徐志超 教授,博士生导师
E-mail: zcxu@nefu.edu.cn
东北林业大学生命科学学院(新逸夫教学楼507)
工作经历
2021-05至现在,东北林业大学,生命科学学院,教授
2016-08至2021-05,中国医学科学院药用植物研究所,助理研究员,副研究员
2019-09至2020-09,VIB - UGent Center for Plant Systems Biology,访问学者
研究领域
林源活性物质代谢合成及调控;合成生物学;本草基因组学;中草药资源开发利用
科研项目(主持)
1. “功效-物质-遗传”关联的五味子优良品质形成机制研究,国自然区域重点(联合)
2. 酪氨酸衍生的中药活性成分异源高效生物制造,国家重点研发计划(任务)
3. 濒危药材关黄柏活性成分小檗碱的生物合成机制研究,国自然面上项目
4. 西红花苷生源途径解析及合成生物学研究,国自然面上项目
5. 中药多组学方法创新及新品种选育研究,国家重点研发计划(课题)
6. 丹参酮生物合成关键酶短链脱氢酶编码基因的克隆和功能鉴定,国自然青年基金
代表性论文(第一及通讯,含共同)
1. Insights into angiosperm evolution and lineage-specialized lignan biosynthesis from the early-diverging Schisandra genome, Science Advances, 2025, 11, eadw0486
2. Convergent evolution of berberine biosynthesis, Science Advances, 2024, 10, eads3596
3. Lineage-specific CYP80 expansion and benzylisoquinoline alkaloid diversity in early-diverging eudicots. Advanced Science, 2024, 2309990
4. Cepharanthine analogs mining and genomes of Stephania accelerate anti-coronavirus drug discovery. Nature Communications, 2024, 15: 1537
5. Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis. Nature Communications, 2023, 14:6470
6. Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genus Salvia. Nature Communications, 2023, 14: 4696
7. Identification, Characterization, and Catalytic Mechanism of Regioselective UbiA Prenyltransferases in Morus Plants. Angewandte Chemie International Edition, 2025, e202504190
8. Resolving floral development dynamics using genome and single-cell temporal transcriptome of Dendrobium devonianum. Plant Biotechnology Journal, 2025, 10.1111/pbi.70094
9. Unveiling the Spatiotemporal Landscape of Ganoderma lingzhi: Insights into Ganoderic Acid Distribution and Biosynthesis. Engineering, 2025, 10.1016/j.eng.2025.03.030
10. Genetic and genomic insights into the dichogamy in Zingiberaceae. Plant Communications, 2025,101352
11. Structural diversity, evolutionary origin, and metabolic engineering of plant specialized benzylisoquinoline alkaloids. Natural Product Reports, 2024, 41:1787-1810
12. Lonicera caerulea genome reveals molecular mechanisms of freezing tolerance and anthocyanin biosynthesis, Journal of Advanced Research, 2024, 10.1016/j.jare.2024.12.038
13. Crocus genome reveals the evolutionary origin of crocin biosynthesis. Acta Pharmaceutica Sinica B, 2024, 14(4):1878-1891
14. Heterologous biosynthesis of saponin adjuvants from Quillaja saponaria: A symbolic achievement in metabolic engineering. Acta Pharmaceutica Sinica B, 2024, 14(12):5518-5520
15. Functional evolution and diversification of the CYP82D subfamily members shape flavonoid diversification in the genus Scutellaria. Plant Communications, 2024, 6(1):101134
16. Herbgenomics: Decipher molecular genetics of medicinal plants, Innovation, 2022, 3(6): 100322
17. Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae. Plant Journal, 2022, 109(5):1305-1318
18. The genome of Corydalis reveals the evolution of benzylisoquinoline alkaloid biosynthesis in Ranunculales. Plant Journal, 2022, 111:217-230
19. The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration. New Phytologist, 2020, 227(3):930-943
20. Genome analysis of the ancient tracheophyte Selaginella tamariscina reveals evolutionary features relevant to the acquisition of desiccation tolerance. Molecular Plant, 2018, 11: 983-994
21. Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis. Plant Journal, 2015, 82:951-961
出版著作及教材
1.《药用植物分子遗传学》科学出版社十四五本科规划教材 2025(主编)
2.《药用植物分子遗传学》科学出版社 2022
3.《本草基因组学-中药组学的发展与未来》 科学出版社 2016
4.《本草基因组学》全国高等医药院校规划教材 科学出版社 2018
5.《药用植物品质生物学》科学出版社 2019
教学及科研奖励
1. 教育部青年长江学者,2024
2. 中医药十大学术进展,中华中医药学会,2024
3. 中国产学研合作创新与促进奖,产学研合作创新成果奖二等奖,2024
4. 黑龙江省高等教育和职业教育教学成果奖,一等奖,2022
5. 世界中医药学会联合会,中医药国际贡献奖科技进步奖,一等奖,2018