徐志超教授，博士生导师
E-mail: zcxu@nefu.edu.cn
东北林业大学生命科学学院（新逸夫教学楼507）
工作经历
2021-05至现在，东北林业大学，生命科学学院，教授
2016-08至2021-05，中国医学科学院药用植物研究所，助理研究员，副研究员
2019-09至2020-09，VIB - UGent Center for Plant Systems Biology，访问学者
研究领域
林源活性物质代谢合成及调控；合成生物学；本草基因组学；分子辅助育种；分子鉴定
科研项目（主持）
1. “功效-物质-遗传”关联的五味子优良品质形成机制研究，国自然区域重点（联合）
2.酪氨酸衍生的中药活性成分异源高效生物制造，国家重点研发计划（任务）
3.濒危药材关黄柏活性成分小檗碱的生物合成机制研究，国自然面上项目
4.西红花苷生源途径解析及合成生物学研究，国自然面上项目
5.中药多组学方法创新及新品种选育研究，国家重点研发计划（课题）
6.丹参酮生物合成关键酶短链脱氢酶编码基因的克隆和功能鉴定，国自然青年基金
代表性论文（第一及通讯，含共同，IF2022）
1. Lineage-specific CYP80 Expansion and Benzylisoquinoline Alkaloid Diversity in Early-diverging Eudicots.Advanced Science, 2024, 2309990 (IF=15.1)
2. Characterization of the horse chestnut genome reveals the evolution of aescin and aesculin biosynthesis.Nature Communications, 2023, 14: 6470 (IF=16.6)Highlight
3. Functional divergence of CYP76AKs shapes the chemodiversity of abietane-type diterpenoids in genusSalvia.Nature Communications, 2023, 14: 4696 (IF=16.6)
4. Cepharanthine analogs mining and genomes ofStephaniaaccelerate anti-coronavirus drug discovery.Nature Communications, 2024, 15: 1537 (IF=16.6)
5. Herbgenomics: Decipher molecular genetics of medicinal plants,Innovation, 2022, 3(6): 100322. (IF=32.1)
6.Crocusgenome reveals the evolutionary origin of crocin biosynthesis.Acta Pharmaceutica Sinica B, 2023 (IF=14.5)
7.Cannabis sativa: origin and history, glandular trichome development, and cannabinoid biosynthesis,Horticulture Research, 2023, uhad150 (IF=8.7)Cover story
8. Genome analysis of the ancient tracheophyteSelaginella tamariscinareveals evolutionary features relevant to the acquisition of desiccation tolerance.Molecular Plant, 2018, 11: 983-994. (IF=27.5)SPOTLIGHT,ESI Highly Cited Paper
9. Advances in pharmacology, biosynthesis, and metabolic engineering ofScutellaria-specialized metabolites,Critical Reviews in Biotechnology, 2024, 44(2):302-318 (IF=9.0)
10. Novel processing strategies to enhance the bioaccessibility and bioavailability of functional components in wheat bran.Critical Reviews in Food Science and Nutrition, 2022, 10.1080/10408398.2022.2129582 (IF=10.2)
11. Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae.Plant Journal, 2022, 109(5):1305-1318 (IF=7.2)
12. The genome ofCorydalisreveals the evolution of benzylisoquinoline alkaloid biosynthesis in Ranunculales.Plant Journal, 2022, 111(1):217-230 (IF=7.2)
13. Trends in Herbgenomics.SCIENCE CHINA Life Sciences, 2019, 62(3): 288-308. (IF=9.1)
14. The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration.New Phytologist, 2020,227(3):930-943.(IF=9.4)
15. Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues ofSalvia miltiorrhizaand tanshinone biosynthesis.Plant Journal, 2015, 82:951-961. (IF=7.2)ESI Highly Cited Paper;TOP5 most cited articles over 2016-2017 (Plant Journal)
16. Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants.BMC Biology, 2020, 18: 63. (IF=5.4)HIGHLIGHT
17. Comparative Genome Analysis ofScutellaria baicalensisandScutellaria barbataReveals the Evolution of Active Flavonoid Biosynthesis.Genomics Proteomics and Bioinformatics, 2020, 18: 230-240. (IF= 9.5)
18. The 2-oxoglutarate-dependent dioxygenase superfamily participates in tanshinone production ofSalvia miltiorrhiza.Journal of Experimental Botany, 2017, 68 (9): 2299-2308. (IF= 6.9)
19. Precise species detection of traditional Chinese patent medicine by shotgun metagenomic sequencing.Phytomedicine,2018, 47: 40-47. (IF=7.9)
20. Genome-wide identification and functional characterization of 2,3-oxidosqualene cyclase genes inPhellodendron amurense.Industrial Crops and Products, 2024, 208, 117721. (IF=5.9)
出版著作
1.《药用植物分子遗传学》科学出版社2022
2.《本草基因组学-中药组学的发展与未来》科学出版社2016
3.《本草基因组学》全国高等医药院校规划教材科学出版社2018
4.《药用植物品质生物学》科学出版社2019
5. “The Genome ofSalvia miltiorrhiza” of《TheSalvia miltiorrhizaGenome》Springer 2019
奖励
1.中草药国际通用DNA条形码鉴定体系，世界中医药学会联合会，中医药国际贡献奖科技进步奖，一等奖，2018
2.黑龙江省高等教育和职业教育教学成果奖一等奖
3.濒危重楼属植物资源种质创新与产业化应用，中国产学研合作创新与促进奖，产学研合作创新成果奖二等奖，2024
授权专利
1.一种基于宏基因组的中成药质量控制方法，2022，美国专利
2.参与西红花苷合成的糖基转移酶GjUGT94E13和GjUGT74F8的筛选鉴定及应用，2022
3.一种参与挥发性成分形成的类胡萝卜素裂解双加氧酶编码基因的筛选鉴定及应用，2022
4.一种参与金银花花色变化的类萝卜素裂解双加氧酶编码基因的筛选鉴定及应用，2022
5.七叶树2,3-氧化鲨烯环化酶及其编码基因与应用，2023
6.催化β-香树脂醇21位羟基化的CYP450酶蛋白及编码基因与应用，2023
